منابع مشابه
The stability of 2-acetoxy-4-trifluoromethylbenzoic acid (Triflusal) in micellar pseudophase.
The new platelet antiaggregant Triflusal or 2-acetoxy-4-trifluoromethylbenzoic acid presents a structural analogy to acetylsalicylic acid (ASA). Alkaline hydrolysis of triflusal was studied in the presence and absence of cationic micelles of N-cetyl-N-ethyl-N,N-dimethylammonium bromide (CDEABr) at different KOH concentrations and different temperatures (25, 30, and 37 degrees C) using a spectro...
متن کاملInhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid.
The therapeutic potential of drugs that block the induction of cyclooxygenase-2 has been emphasized. When two 4-trifluoromethyl salicylate derivatives [2-acetoxy-4-trifluoromethyl-benzoic acid (triflusal) and its deacetylated metabolite 2-hydroxy-4-trifluoromethylbenzoic acid (HTB)] were compared with aspirin and sodium salicylate as cyclooxygenase-2 (COX-2) inhibitors, we observed that in bact...
متن کاملElectrochemical Study of Iodide in the Presence of 2-Thiobarbituric Acid-Catalytic Determination of 2-Thiobarbituric Acid
Electrochemical oxidation of iodide has been studied in the presence of 2-thioborbituric acid using cyclic voltammetry and controlled-potential coulometry. The results indicate that, the resulting iodine takes part in halogenations reaction with 2-thiobarbituric acid. In addition, the present data are indicative of the suitability of iodide as a quasi mediator for determination of 2-thiobar...
متن کامل2-(2-Bromophenyl)acetic acid
In the title mol-ecule, C(8)H(7)BrO(2), the carboxyl group is twisted by 76.2 (3)° from the benzene ring plane. In the crystal, mol-ecules are linked into inversion dimers through pairs of O-H⋯O hydrogen bonds. The dimers are further linked into layers parallel to the bc plane by weak C-H⋯O hydrogen bonds.
متن کامل2-(2-Pyridylsulfanyl)acetic acid
All non-H atoms of the title compound, C(7)H(7)NO(2)S, lie on a crystallographic mirror plane, with the two methyl-ene H atoms bis-ected by this plane. The crystal packing is characterized by inter-molecular C-H⋯O and O-H⋯N contacts, which link the mol-ecules into infinite zigzag chains parallel to [010].
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2011
ISSN: 1600-5368
DOI: 10.1107/s1600536811009597